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Lactoferrin for Prevention of Sepsis in Infants

Overview

The high frequency of serious infections in premature infants, as well as their associated morbidity and mortality, is the critical barrier to progress in improving infant care. We hypothesize that lactoferrin is the major factor in milk responsible for these protective effects (decreased rates of infection  and improved neurodevelopment) due to its antimicrobial, anti-inflammatory and immunomodulatory properties.  This study if successful will fundamentally change current clinical care of neonates both in the developed and developing world, and could improve the quality of life of the infants and their families.